| NCT03499795 |
VGX-3100 Delivered Intramuscularly (IM) Followed by Electroporation (EP) for the Treatment of HPV-16 and/or HPV-18 Related Anal or Anal/Peri-Anal, High Grade Squamous Intraepithelial Lesion (HSIL) in Individuals Seronegative for Human Immunodeficiency Virus (HIV)-1/2 |
https://ClinicalTrials.gov/show/NCT03499795 |
Active, not recruiting |
Inovio Pharmaceuticals |
2021-05-31 |
| NCT03381352 |
Study of IMRT Radiotherapy Concurrent Chemothrerapy for Anal Cancer |
https://ClinicalTrials.gov/show/NCT03381352 |
Recruiting |
Chinese Academy of Medical Sciences |
2018-12-31 |
| NCT03357757 |
Avelumab With Valproic Acid in Virus-associated Cancer |
https://ClinicalTrials.gov/show/NCT03357757 |
Recruiting |
AHS Cancer Control Alberta |
2022-03-30 |
| NCT03302858 |
A Safety and Efficacy Trial of Circumferential Anal Canal Radiofrequency Ablation for High-Grade Anal Intraepithelial Neoplasia Using the BARRXâ„¢ Anorectal Wand |
https://ClinicalTrials.gov/show/NCT03302858 |
Recruiting |
Laser Surgery Care |
2019-10-31 |
| NCT03221400 |
PEN-866 in Patients With Advanced Solid Malignancies |
https://ClinicalTrials.gov/show/NCT03221400 |
Recruiting |
Tarveda Therapeutics |
2021-12-31 |
| NCT03202992 |
Study of Topical ABI-1968 in Subjects With Precancerous Anal Lesions Resulting From Human Papillomavirus (HPV) Infection |
https://ClinicalTrials.gov/show/NCT03202992 |
Completed |
Antiva Biosciences |
2019-02-04 |
| NCT03113942 |
Study of Pomalidomide in Anal Cancer Precursors |
https://ClinicalTrials.gov/show/NCT03113942 |
Active, not recruiting |
Kirby Institute |
2019-03-31 |
| NCT03061435 |
Screening for Anal Cancer in Women With High-grade Vulvar Dysplasia or Vulvar Cancer. |
https://ClinicalTrials.gov/show/NCT03061435 |
Recruiting |
Sunnybrook Health Sciences Centre |
2020-12-31 |
| NCT03233711 |
Nivolumab After Combined Modality Therapy in Treating Patients With High Risk Stage II-IIIB Anal Cancer |
https://ClinicalTrials.gov/show/NCT03233711 |
Recruiting |
National Cancer Institute (NCI) |
2021-12-30 |
| NCT03018418 |
Proton Therapy in Reducing Toxicity in Anal Cancer |
https://ClinicalTrials.gov/show/NCT03018418 |
Recruiting |
University of Cincinnati |
2022-06-30 |
| NCT02981862 |
CaptHPV : Validation of the Method “CaptHPV” for the Diagnosis of Human Papillomavirus Associated Infiltrating Carcinomas |
https://ClinicalTrials.gov/show/NCT02981862 |
Completed |
Institut de Cancérologie de Lorraine |
2018-06-12 |
| NCT02865135 |
Trial To Test Safety And Efficacy Of Vaccination For Incurable HPV 16-Related Oropharyngeal, Cervical And Anal Cancer |
https://ClinicalTrials.gov/show/NCT02865135 |
Active, not recruiting |
Dana-Farber Cancer Institute |
2020-12-31 |
| NCT02816879 |
Anal Cytology Collection Procedures in Predicting High-Grade Anal Dysplasia in Men Who Have Sex With Men |
https://ClinicalTrials.gov/show/NCT02816879 |
Active, not recruiting |
Jonsson Comprehensive Cancer Center |
2020-07-31 |
| NCT02785263 |
Shared Decision Making With Anal Cancer Patients on Radiation Dose |
https://ClinicalTrials.gov/show/NCT02785263 |
Recruiting |
Vejle Hospital |
2021-03-31 |
| NCT02701088 |
Study of SIB-IMRT in Combination With 5-FU and Mitomycin-C Among Patients With Locally Advanced Anal Canal Cancer: Efficacy, Safety and Quality of Life |
https://ClinicalTrials.gov/show/NCT02701088 |
Recruiting |
Centre Francois Baclesse |
2020-12-31 |
| NCT02560298 |
Cisplatin and Fluorouracil Compared With Carboplatin and Paclitaxel in Treating Patients With Inoperable Locally Recurrent or Metastatic Anal Cancer |
https://ClinicalTrials.gov/show/NCT02560298 |
Active, not recruiting |
Eastern Cooperative Oncology Group |
2020-08-31 |
| NCT02526953 |
Efficacy Study of Chemoradiotherapy With or Without Paclitaxel in Squamous-cell Anal Carcinoma Patients |
https://ClinicalTrials.gov/show/NCT02526953 |
Enrolling by invitation |
Blokhin’s Russian Cancer Research Center |
2021-10-31 |
| NCT02503111 |
The HPV-SAVE Study Team: HPV Screening and Vaccine Evaluation in Men Who Have Sex With Men |
https://ClinicalTrials.gov/show/NCT02503111 |
Enrolling by invitation |
University Health Network, Toronto |
2020-11-30 |
| NCT02489422 |
Programs To Support You During Chemotherapy |
https://ClinicalTrials.gov/show/NCT02489422 |
Completed |
Wake Forest University Health Sciences |
2020-01-31 |
| NCT02437851 |
Surgery in Treating Patients With Early Stage Anal Canal or Perianal Cancer and HIV Infection |
https://ClinicalTrials.gov/show/NCT02437851 |
Active, not recruiting |
AIDS Malignancy Consortium |
2025-08-31 |
| NCT02402842 |
Clinical and Biological Interest of Taxanes in Advanced Squamous Cell Anal Carcinoma |
https://ClinicalTrials.gov/show/NCT02402842 |
Active, not recruiting |
Centre Hospitalier Universitaire de Besancon |
2018-06-30 |
| NCT02399813 |
Phase 2 Study of ADXS11-001 in Subjects With Carcinoma of the Anorectal Canal |
https://ClinicalTrials.gov/show/NCT02399813 |
Completed |
Advaxis, Inc. |
2017-06-30 |
| NCT02384005 |
The Feasibility of Self or Partner-assisted Digital Anal Exam Screening |
https://ClinicalTrials.gov/show/NCT02384005 |
Completed |
The University of Texas Health Science Center, Houston |
2016-04-30 |
| NCT02379520 |
HPV-16/18 E6/E7-Specific T Lymphocytes, Relapsed HPV-Associated Cancers, HESTIA |
https://ClinicalTrials.gov/show/NCT02379520 |
Recruiting |
Baylor College of Medicine |
2020-10-31 |
| NCT02369939 |
Effects of Deep Regional Hyperthermia in Patients With Anal Carcinoma Treated by Standard Radiochemotherapy |
https://ClinicalTrials.gov/show/NCT02369939 |
Recruiting |
University of Erlangen-Nürnberg Medical School |
2017-12-31 |
| NCT03386500 |
Safety Study of BMX-001 (Radio-protector) in Patients With Newly Diagnosed Anal Cancer |
https://ClinicalTrials.gov/show/NCT03386500 |
Recruiting |
University of Nebraska |
2021-12-31 |
| NCT02280811 |
T Cell Receptor Immunotherapy Targeting HPV-16 E6 for HPV-Associated Cancers |
https://ClinicalTrials.gov/show/NCT02280811 |
Completed |
National Institutes of Health Clinical Center (CC) |
2016-06-28 |
| NCT02199236 |
Dose Escalation Trial of Endoluminal High-Dose-Rate Brachytherapy With Concurrent Chemotherapy for Rectal or Anal Cancer in Patients With Recurrent Disease or Undergoing Non-Operative Management |
https://ClinicalTrials.gov/show/NCT02199236 |
Recruiting |
Memorial Sloan Kettering Cancer Center |
2021-07-31 |
| NCT02140021 |
Biospecimen Collection and Testing for the Prevalence of Anal Dysplasia and Anal Cancer in Patients With Cervical, Vaginal and Vulvar Dysplasia and Cancer |
https://ClinicalTrials.gov/show/NCT02140021 |
Recruiting |
M.D. Anderson Cancer Center |
2020-10-31 |
| NCT01285778 |
Vectibix for the Treatment of Anal Cancer |
https://ClinicalTrials.gov/show/NCT01285778 |
Completed |
Grupo Espanol Multidisciplinario del Cancer Digestivo |
2017-03-24 |
| NCT01946139 |
Anal HPV Tests in Screening for Cell Changes in the Anus in Patients With HIV |
https://ClinicalTrials.gov/show/NCT01946139 |
Completed |
AIDS Malignancy Consortium |
2018-10-31 |
| NCT01717391 |
[F-18] Fluorothymidine PET/CT Imaging for Pelvic Cancers |
https://ClinicalTrials.gov/show/NCT01717391 |
Completed |
University of Iowa |
2016-02-29 |
| NCT01621217 |
Phase I Study of Cetuximab in Combination With 5-fluoruracil, Mitomycin C and Radiotherapy in Patients With Anal Cancer Stage T2 (>4 cm) - T4 N0-3 M0 or Any T N2-3 M0 |
https://ClinicalTrials.gov/show/NCT01621217 |
Completed |
Lund University Hospital |
2020-01-31 |
| NCT01585428 |
Immunotherapy Using Tumor Infiltrating Lymphocytes for Patients With Metastatic Human Papillomavirus-Associated Cancers |
https://ClinicalTrials.gov/show/NCT01585428 |
Completed |
National Institutes of Health Clinical Center (CC) |
2016-04-09 |
| NCT01581840 |
Radiochemotherapy With Panitumumab in the Localised Epidermoid Carcinoma of the Anus |
https://ClinicalTrials.gov/show/NCT01581840 |
Active, not recruiting |
Federation Francophone de Cancerologie Digestive |
2018-09-30 |
| NCT01526486 |
Videoscopic Versus Open Inguinal Lymphadenectomy for Cancer |
https://ClinicalTrials.gov/show/NCT01526486 |
Completed |
Emory University |
2013-02-28 |
| NCT04287868 |
Combination Immunotherapy in Subjects With Advanced HPV Associated Malignancies |
https://ClinicalTrials.gov/show/NCT04287868 |
Recruiting |
National Institutes of Health Clinical Center (CC) |
2021-07-30 |
| NCT04230759 |
Radiochemotherapy +/- Durvalumab for Locally-advanced Anal Carcinoma. A Multicenter, Randomized, Phase II Trial of the German Anal Cancer Study Group |
https://ClinicalTrials.gov/show/NCT04230759 |
Recruiting |
Goethe University |
2023-03-31 |
| NCT04166318 |
Lower-Dose Chemoradiation in Treating Patients With Early-Stage Anal Cancer, the DECREASE Study |
https://ClinicalTrials.gov/show/NCT04166318 |
Recruiting |
Eastern Cooperative Oncology Group |
2025-07-01 |
| NCT04094454 |
Intrafractional Vaginal Dilation in Anal Cancer Patients Undergoing Pelvic Radiotherapy |
https://ClinicalTrials.gov/show/NCT04094454 |
Recruiting |
University Hospital Heidelberg |
2023-10-31 |
| NCT04066894 |
Sacral Nerve Stimulation in Treating Low Anterior Resection Syndrome or Fecal Incontinence in Patients With Locally Advanced Rectal Cancer or Other Pelvic Cancer, the RESTORE Study |
https://ClinicalTrials.gov/show/NCT04066894 |
Recruiting |
M.D. Anderson Cancer Center |
2025-07-31 |
| NCT03983174 |
Drainage Seton With Flap Versus EAS Preserving Seton in Treatment of Transsphincteric Anal Fistula |
https://ClinicalTrials.gov/show/NCT03983174 |
Completed |
Mansoura University |
2018-04-30 |
| NCT03894618 |
SL-279252 (PD1-Fc-OX40L) in Subjects With Advanced Solid Tumors or Lymphomas |
https://ClinicalTrials.gov/show/NCT03894618 |
Recruiting |
Shattuck Labs, Inc. |
2022-02-02 |
| NCT03346915 |
Integrating a Health Information Technology System for Primary and Secondary Cervical Cancer Prevention |
https://ClinicalTrials.gov/show/NCT03346915 |
Completed |
Boston Medical Center |
2019-04-19 |
| NCT03519295 |
A Study of mDCF in Combination or Not With Atezolizumab in Advanced Squamous Cell Anal Carcinoma |
https://ClinicalTrials.gov/show/NCT03519295 |
Recruiting |
GERCOR - Multidisciplinary Oncology Cooperative Group |
2020-06-30 |
| NCT03517488 |
A Study of XmAb®20717 in Subjects With Selected Advanced Solid Tumors |
https://ClinicalTrials.gov/show/NCT03517488 |
Recruiting |
Xencor, Inc. |
2020-12-31 |
| NCT03439085 |
DNA Plasmid-encoding Interleukin-12/HPV DNA Plasmids Therapeutic Vaccine INO-3112 and Durvalumab in Treating Patients With Recurrent or Metastatic Human Papillomavirus Associated Cancers |
https://ClinicalTrials.gov/show/NCT03439085 |
Recruiting |
M.D. Anderson Cancer Center |
2020-01-31 |
| NCT03427411 |
M7824 in Subjects With HPV Associated Malignancies |
https://ClinicalTrials.gov/show/NCT03427411 |
Recruiting |
National Institutes of Health Clinical Center (CC) |
2021-12-31 |
| NCT01209325 |
Vaccine Therapy in Preventing Human Papillomavirus Infection in Young HIV-Positive Male Patients Who Have Sex With Males |
https://ClinicalTrials.gov/show/NCT01209325 |
Completed |
AIDS Malignancy Consortium |
2017-12-12 |
| NCT01170299 |
Low-Fiber Diet or High-Fiber Diet in Preventing Bowel Side Effects in Patients Undergoing Radiation Therapy for Gynecological Cancer, Bladder Cancer, Colorectal Cancer, or Anal Cancer |
https://ClinicalTrials.gov/show/NCT01170299 |
Completed |
National Cancer Institute (NCI) |
2012-12-31 |
| NCT01164722 |
Infrared Coagulator Ablation or Observation in Preventing Anal Cancer in HIV-Positive Patients With Anal Neoplasia |
https://ClinicalTrials.gov/show/NCT01164722 |
Completed |
AIDS Malignancy Consortium |
2015-07-31 |
| NCT01104181 |
Hybrid Capture 2 Human Papiloma Virus (HPV) High-Risk Anal DNA Test |
https://ClinicalTrials.gov/show/NCT01104181 |
Completed |
Laser Surgery Care |
2010-12-31 |
| NCT00955591 |
Comparing Two Types of Swabs in Collecting Cell Samples for Anal Pap Tests and Human Papillomavirus Tests in Men Who Have Sex With Men |
https://ClinicalTrials.gov/show/NCT00955591 |
Completed |
Jonsson Comprehensive Cancer Center |
2011-12-12 |
| NCT03870607 |
Prebiotics and Probiotics During Definitive Treatment With Chemotherapy-radiotherapy SCC of the Anal Canal (BISQUIT) |
https://ClinicalTrials.gov/show/NCT03870607 |
Recruiting |
AC Camargo Cancer Center |
2022-08-13 |
| NCT04157985 |
Evaluation of the Length of Treatment With PD-1/PD-L1 Inhibitors in Patients With Advanced Solid Tumors |
https://ClinicalTrials.gov/show/NCT04157985 |
Recruiting |
University of Pittsburgh |
2021-10-31 |
| NCT03944252 |
Cetuximab + Avelumab or Avelumab Alone for Unresectable, Locally Advanced or Metastatic Squamous Cell Anal Carcinoma (SCCAC) Progressed After at Least One Line of Systemic Treatment (CARACAS) |
https://ClinicalTrials.gov/show/NCT03944252 |
Active, not recruiting |
Gruppo Oncologico del Nord-Ovest |
2021-02-28 |
| NCT03690921 |
LET-IMPT and Standard Chemotherapy in Treating Patients With Newly Diagnosed Stage I-III Anal Canal Squamous Cell Cancer |
https://ClinicalTrials.gov/show/NCT03690921 |
Recruiting |
M.D. Anderson Cancer Center |
2022-05-23 |
| NCT01651949 |
Multivalent HPV (Human Papillomavirus) Vaccine Study in 16- to 26-Year Old Men and Women (V503-003) |
https://ClinicalTrials.gov/show/NCT01651949 |
Completed |
Merck Sharp & Dohme Corp. |
2014-08-04 |
| NCT04234113 |
Study of SO-C101 and SO-C101in Combination With Pembro in Adult Patients With Advanced/Metastatic Solid Tumors |
https://ClinicalTrials.gov/show/NCT04234113 |
Recruiting |
Sotio a.s. |
2022-03-31 |
| NCT02919969 |
Pembrolizumab in Refractory Metastatic Anal Cancer |
https://ClinicalTrials.gov/show/NCT02919969 |
Recruiting |
Dana-Farber Cancer Institute |
2020-03-31 |
| NCT00654160 |
Irinotecan, Fluorouracil, and Leucovorin in Treating Patients With Advanced Gastrointestinal Cancer |
https://ClinicalTrials.gov/show/NCT00654160 |
Completed |
Mayo Clinic |
2010-11-30 |
| NCT00622440 |
Treatment of Anal High-grade Squamous Intraepithelial Lesions (HSIL) Through Use of a Chinese Herbal Topical Cream |
https://ClinicalTrials.gov/show/NCT00622440 |
Completed |
University of California, San Francisco |
2012-12-12 |
| NCT00428285 |
Tolerability, Safety, & Efficacy of Argon Plasma Coagulation to Treat Anal Intraepithelial Neoplasia in HIV-Positive Men |
https://ClinicalTrials.gov/show/NCT00428285 |
Completed |
Centre hospitalier de l’Université de Montréal (CHUM) |
2010-02-28 |
| NCT00423293 |
Intensity-Modulated Radiation Therapy, Fluorouracil, and Mitomycin C in Treating Patients With Invasive Anal Cancer |
https://ClinicalTrials.gov/show/NCT00423293 |
Completed |
Radiation Therapy Oncology Group |
2009-02-28 |
| NCT00397384 |
Erlotinib Hydrochloride and Cetuximab in Treating Patients With Advanced Gastrointestinal Cancer, Head and Neck Cancer, Non-Small Cell Lung Cancer, or Colorectal Cancer |
https://ClinicalTrials.gov/show/NCT00397384 |
Completed |
National Cancer Institute (NCI) |
2013-06-30 |
| NCT00324415 |
Combined Modality Therapy for Patients With With HIV and Stage I, Stage II, or Stage III Anal Cancer |
https://ClinicalTrials.gov/show/NCT00324415 |
Completed |
AIDS Malignancy Consortium |
2014-04-30 |
| NCT00316888 |
Cetuximab, Cisplatin, Fluorouracil, and Radiation Therapy in Treating Patients With Anal Cancer |
https://ClinicalTrials.gov/show/NCT00316888 |
Active, not recruiting |
Eastern Cooperative Oncology Group |
2015-11-30 |
| NCT00093379 |
Capecitabine, Oxaliplatin, and Radiation Therapy in Treating Patients With Stage II or Stage III Anal Cancer |
https://ClinicalTrials.gov/show/NCT00093379 |
Completed |
M.D. Anderson Cancer Center |
2012-07-31 |
| NCT00003427 |
Oxaliplatin Plus Irinotecan in Treating Patients With Metastatic Gastrointestinal Cancer |
https://ClinicalTrials.gov/show/NCT00003427 |
Completed |
Memorial Sloan Kettering Cancer Center |
2002-04-30 |
| NCT00003046 |
Interleukin-12 in Treating Patients With Cancer in the Abdomen |
https://ClinicalTrials.gov/show/NCT00003046 |
Completed |
M.D. Anderson Cancer Center |
2001-10-31 |
| NCT00075868 |
Octreotide in Preventing or Reducing Diarrhea in Patients Receiving Chemoradiotherapy for Anal or Rectal Cancer |
https://ClinicalTrials.gov/show/NCT00075868 |
Completed |
Radiation Therapy Oncology Group |
2006-08-31 |
| NCT00004074 |
Interleukin-12 and Trastuzumab in Treating Patients With Cancer That Has High Levels of HER2/Neu |
https://ClinicalTrials.gov/show/NCT00004074 |
Completed |
National Cancer Institute (NCI) |
2009-02-28 |
| NCT00066430 |
Infrared Coagulation in Preventing Anal Cancer in Patients With HIV Who Have Anal Neoplasia |
https://ClinicalTrials.gov/show/NCT00066430 |
Completed |
AIDS Malignancy Consortium |
2004-09-30 |
| NCT00059891 |
Anal Sphincter Prosthesis in Treating Patients Who Are Undergoing Surgery for Anal or Rectal Cancer |
https://ClinicalTrials.gov/show/NCT00059891 |
Completed |
Memorial Sloan Kettering Cancer Center |
2009-10-31 |
| NCT00052897 |
SGN-00101 in Preventing Anal Cancer in Patients With HIV Who Have Anal Neoplasia |
https://ClinicalTrials.gov/show/NCT00052897 |
Completed |
National Cancer Institute (NCI) |
2005-07-31 |
| NCT00031681 |
7-Hydroxystaurosporine and Irinotecan Hydrochloride in Treating Patients With Metastatic or Unresectable Solid Tumors or Triple Negative Breast Cancer (Currently Accruing Only Triple-negative Breast Cancer Patients Since 6/8/2007) |
https://ClinicalTrials.gov/show/NCT00031681 |
Completed |
National Cancer Institute (NCI) |
2011-01-31 |
| NCT00030498 |
Erlotinib in Treating Patients With Solid Tumors and Liver or Kidney Dysfunction |
https://ClinicalTrials.gov/show/NCT00030498 |
Completed |
National Cancer Institute (NCI) |
2007-07-31 |
| NCT00025090 |
Radiation Therapy Plus Fluorouracil With or Without Additional Chemotherapy in Treating Patients With Primary Anal Cancer |
https://ClinicalTrials.gov/show/NCT00025090 |
Completed |
National Cancer Institute (NCI) |
NA |
| NCT00019110 |
Vaccine Therapy in Treating Patients With Advanced or Recurrent Cancer |
https://ClinicalTrials.gov/show/NCT00019110 |
Completed |
National Cancer Institute (NCI) |
NA |
| NCT00003596 |
Chemotherapy Plus Radiation Therapy in Treating Patients With Stage II or Stage III Anal Cancer |
https://ClinicalTrials.gov/show/NCT00003596 |
Completed |
Radiation Therapy Oncology Group |
2005-10-31 |
| NCT00550589 |
Cidofovir in Treating HIV-Infected Patients With High-Grade Squamous Intraepithelial Lesions of the Skin Near the Anus |
https://ClinicalTrials.gov/show/NCT00550589 |
Completed |
AIDS Malignancy Consortium |
2010-02-28 |
| NCT00000764 |
Chemoprevention of Anal Neoplasia Arising Secondary to Anogenital Human Papillomavirus Infection in Persons With HIV Infection. |
https://ClinicalTrials.gov/show/NCT00000764 |
Completed |
National Institute of Allergy and Infectious Diseases (NIAID) |
NA |